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, ( ), , . . , , , . . , +, , () () . (, ) (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5), (Grard et al., 2007; Tuplin et al., 2011). 5' 3' - , , , - - , . , , (Thurner et al., 2004). , . (Firth, Atkins, 2009). , , (Marin, 1995; Tuplin et al., 2011), . , , .

, , .

. , , EMBL ( : 062063, 062064, 507800, AF069066, AF253419, AF253420, AF527415, 600965, AY169390, AY182009, AY193805, AY217093, AY323490, AY438626, DQ153877, DQ401140, DQ486861, DQ862460, DQ989336, EF469661, EF469662, EU480689, EU543649, EU670438, EU770575, EU790644, EU816450, EU816451, EU816452, EU816453, EU816454, EU816455, FJ402885, FJ402886, FJ572210, FJ906622, FJ968751, FJ997899, GQ228395, GQ266392, GU121642, 055369, 120875, 440558, 440559, 440560, 440561, 440562, 440563, 535610, 535611, 859894, 859895, HQ201303, JF316707, JF316708, L06436, 0361, U27491, U27495,U39292).

ClustalX (1.8) ( (Multiple Alignments) GAP OPENING=20, DELAY DIVERGENT SEQUENCES=30 %, TRANSITION WEIGHT=0,6; (Neighbour Joining), bootstrap replicates > 1000).

(, , 2003; , , 2008). , .. , 3' - , . - MJ. MJ 2, MJmin, . , . i MJij .

. , , (n = 841) , , , (43) G ( 2489 600965), , NS1. , . , NS1 , NS4A, (Lindenbach, Rice, 1999), , , .

. , . , , (Hiplin et al., 2011) 1-330 ( 133-135 , - .) , , (Tuplin et al., 2011) SL4 (140 .), SL6 (217 ., 219 .), , (299 .).

(Tuplin et al., 2011), SL6, , . , , , . , . , 217 . 219 ., , , , NS3, NS4B, NS5. , SL4 (140 .), , (299 .).

, (Tuplin et al., 2011) , SL6, . , ( 217 . 219 .). , - , .. . , -21 ( ), , (Mandi et al., 2001).

, , .

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